5 Simple Techniques For https://www.ceesdekker.net
5 Simple Techniques For https://www.ceesdekker.net
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Halfway as a result of his occupation, Cees Dekker reinvented himself. Following decades of hardcore physics, he shifted his target to ‘nanobiology’ at the change of your millennium. A expression he coined himself, as a subject of simple fact.
Our group research bacterial mobile division and is particularly aiming to represent a ‘bottom up biology’ in artificial cells that may autonomously divide. Our main curiosity lies in mobile division, chromatin construction, and spatial Handle.
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I'm able to barely picture how I, as being a geneticist, would have the ability to discover fundamental physics, not to mention contend at the highest. How did you go about this?
2010, formulated a new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into solid-state nanopores
Our study ranges from your biophysics of DNA to synthetic cells and past. Make sure you have a look below at the spectrum of our current projects.
All parameters have been the exact same for every panel in this video, except for the Preliminary placement on the 6hb rod (demonstrated in blue) to the nanopore. Simulations that terminated early due to translocation from the rod with the pore are marked by a grey track record.
2011, first in vitro measurements of transportation throughout an individual biomimetic nuclear pore sophisticated; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and resolved the system of homology recognition in DNA homologous recombination
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Extremely interesting, but that wasn’t really the place my desire lay. I desired to pioneer And that i experienced the sensation that was now not possible, since the most appealing essential insights had presently been uncovered. But my subject experienced created a lot of remarkable new resources to measure particular person molecules. I made a decision that I desired to use this to biology, to take a look at it from the Actual physical standpoint.’
Testing pseudotopological and nontopological styles for SMC-pushed DNA loop extrusion towards roadblock-traversal experiments
1999, first measurement on the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for just a new Luttinger description of interacting electrons in nanotubes
2005, discovery from the system of DNA uncoiling by topoisomerase enzymes; discovery of long-selection conformational modifications in Mre11/DNA repair service complexes; and very first drive measurements on the DNA molecule in a nanopore
Finally, I will briefly sketch a few of our Tips to check out the making of artificial cells, especially our 1st techniques to determine artificial mobile division.